For the past several years, the Muslim Student Union (MSU), the Muslim student group at UC Irvine (UCI), has staged many anti-Israel events, including a large event every spring with some of the most anti-Semitic speakers participating regularly, including the anti-Semitic leaders of the Sabiqun movement. MSU's annual events have included lectures and outdoor displays, and employed provocative titles such as "Israeli Apartheid Week," "Israel: The Politics of Genocide," "Never Again? Palestinian Holocaust" and "Holocaust in the Holy Land."

MSU currently faces a yearlong suspension after UCI concluded that the group planned disruptions of a speech by Israeli Ambassador Michael Oren in February 2010. Approximately 100 individuals repeatedly interrupted Oren's talk, accusing him of murder and shouting, among other things, "How many Palestinians have you killed?" and "Propagating murder is not an expression of free speech." Eleven students—9 from UCI and 2 UC Riverside—were arrested in connection with the disruption. At one point during the talk, Oren was escorted out of the room by security.

The university's investigation into the matter uncovered evidence that MSU organized a calculated demonstration at Ambassador Oren's speech in violation of university policy against disorderly conduct, obstructing university activities, furnishing false information and other campus policies.

Over the years, MSU has distributed radical and anti-Semitic literature through Al Kalima, UCI's Muslim student paper. For example, one editorial published in June 2004 praised Hamas and justified its use of terror by arguing that it is directed against "the evils of Shaytan (Satan) and the enemies of Allah." It argued that the "only solution to the Zionist situation is through military force, which is espoused by Hamas, Hezbollah, Islamic Jihad, and other Islamic resistance organizations."

Together with al-Talib, a sister publication of Muslim students at UCLA, Al Kalima also produces brochures that employ Islamist militant language. One of these, a colorful glossy leaflet handed out in 2009, advocated jihad and martyrdom, explaining that "the individual or community that participates in jihad finds itself between two blissful outcomes, either victory and the establishment of justice, or the reward of martyrdom and Paradise."